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2008 Robert Cary (Novel Immunocapture …..)

Novel Immunocapture Technology for Field Deployable Nucleic Acid-Based Detection of Citrus Pathogens

The primary hypothesis guiding this project is that a highly simplified and field deployable sample preparation system can be realized using low cost and easily used lateral flow chromatography technologies. Specifically, we proposed the development of a nucleic acid analysis system making use of Lateral Flow Microarray technology (LFM) and supporting field deployable sample preparation and amplification methods. Toward this end we are developing and testing lateral flow chromatographic immuno-capture methods, novel passive fluid exchange systems, and integration of these systems to form the basis of a field deployable diagnostic platform.